breath

breath

during bronchoscopy

during bronchoscopy

Bronchal Carcinoma

Differentiation Bronchial Carcinoma / Healthy

Breath analysis by IMS can detect a discriminating combination of VOCs in patients with lung cancer. By pattern recognition without the need for chemical analysis of the underlying VOCs, IMS has the potential to facilitate lung cancer diagnosis. 

Publications

  • Handa, Hiroshi; Usuba, Ayano; Maddula, Sasidhar; Baumbach, Jörg Ingo; Mineshita, Masamichi; Miyazawa, Teruomi;Exhaled Breath Analysis for Lung Cancer Detection Using Ion Mobility SpectrometryPLoS ONE 9, 12 (2014) 1-1310.1371/journal.pone.0114555
  • Baumbach, J.I.; Maddula, S.; Sommerwerck, U.; Besa, V.; Kurth, I.; Bödeker, B.; Teschler, H.; Freitag, L.; Darwiche, K.;Significant different volatile biomarker during bronchoscopic ion mobility spectrometry investigation of patients suffering lung carcinomaInt. J. Ion Mobility Spectrom. 14, 4 (2011) 159-16610.1007/s12127-011-0078-5
  • Baumbach, J.I.; Maddula, S.; Bödeker, B.; Westhoff, M.; Litterst, P.; Davies, A.N.; Neuziel, P.;Breath Discovery based on Ion Mobility Spectrometry and Classification and Differentiation Models for Lung DiseasesBiomedizinische Technik 55, Suppl. 1 (2010)DOI 10.1515/BMT.2010.537
  • Westhoff, M.; Litterst, P.; Freitag, L.; Urfer, W.; Bader, S.; Baumbach, J. I.;Ion mobility spectrometry for the detection of volatile organic compounds in exhaled breath of patients with lung cancer: results of a pilot studyThorax FIELD Full Journal Title:Thorax 64, 9 (2009) 744-810.1136/thx.2008.099465
  • Westhoff, M.; Litterst, P.; Freitag, L.; Urfer, W.; Bader, S.; Baumbach, J.I.;Ion mobility spectrometry for the detection of volatile organic compounds in exhaled breath of patients with lung cancer: results of a pilot studyThorax 64, (2009) 744 - 748
  • Davies, A. N.; Baumbach, J.I.;Early lung cancer diagnostics by ion mobility spectrometry data handlingSpectroscopy Europe 20, 5 (2008) 18-21
  • Baumbach, J.; Bunkowski, A.; Lange, S.; Oberwahrenbrock, T.; Kleinboelting, N.; Rahmann, S.; Baumbach, J.I.;IMS2 -- An integrated medical software system for early lung cancer detection using ion mobility spectrometry data of human breathJournal of Integrative Bioinformatics 4, 3 (2007) 75:1-12
  • Baumbach, J. I.; Westhoff, M.;Ion mobility spectrometry to detect lung cancer and airway infectionsSpectroscopy Europe 18, 6 (2006) 22-27
  • Baumbach, Joerg Ingo; Vautz, Wolfgang; Ruzsanyi, Vera; Freitag, Lutz;Early detection of lung cancer: Metabolic profiling of human breath with ion mobility spectrometers3, (2005) 1343-1358
  • Ruzsanyi, V.; Sielemann, S.; Baumbach, J. I.;Determination of VOCs in human breath using IMSInt. J. Ion Mobility Spectrom. 5 (3), 3 (2002) 45-48
  • Baumbach, J. I.;Lungenkrebsfrüherkennung mittels IonenbeweglichkeitsspektrometrieUni-Report 33, (2001) 44-48
  • Horsch, S.; Kopczynski, D.; Kuthe, E.; Baumbach, J.I.; Rahmann, S.; Rahnenfuehrer, J.A detailed comparison of analysis processes for MCC-IMS data in disease classification - Automated methods can replace manual peak annotationsPLOS ONE 12, 9 (2017) e018432110.1371/journal.pone.0184321